Could an old antibiotic tame ulcerative colitis?

NCT ID NCT06201793

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study tested whether adding the antibiotic minocycline to standard mesalamine treatment helps control mild-to-moderate ulcerative colitis. 46 adults took part. Researchers measured disease activity using a symptom score. The trial is complete, but results are not yet published.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
minocycline (an antibiotic) added to standard mesalamine treatment
What this could lead to
If it works, adding minocycline could help control ulcerative colitis symptoms better than mesalamine alone.
What could go wrong
This is a small, early-phase trial with only 46 people. Results may not apply to everyone, and minocycline can cause side effects like dizziness or antibiotic resistance.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Faculty of Medicine, Mansoura University

    Al Mansurah, 7650001, Egypt

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