Old antibiotic, new trick: could minocycline tame resistant hypertension?
NCT ID NCT06246396
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether the antibiotic minocycline can lower blood pressure in people whose hypertension does not respond to standard treatments. Researchers will give 120 adults either minocycline or a placebo daily for three months to see if the drug works by changing gut bacteria, reducing inflammation, or calming overactive immune signals. The goal is to find a new way to control resistant hypertension, not to cure it.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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UF Clinical Research Center (UF CRC) - CTSI
RECRUITINGGainesville, Florida, 32610, United States
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