Can mindfulness lower heart risk in older HIV patients?

NCT ID NCT06001814

Recruiting now Symptom relief Sponsor: Massachusetts General Hospital Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 26, 2026 · Updated 1 time

Summary

This study tests a program called One-Mind One-Heart that combines mindfulness and behavior change skills to help older adults with HIV reduce stress and improve heart health. The program includes text messages and covers topics like physical activity, diet, and substance use. The study will enroll 50 people aged 50 and older with HIV and high stress levels to see if the program is feasible and acceptable.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: mindfulness and behavior change program (One-Mind One-Heart)
What this could lead to: If it works, this could point toward a simple, low-cost way to lower heart disease risk in older people with HIV by reducing stress and promoting healthy habits.
What could go wrong: This is a very early, small pilot study with only 50 participants. It is designed to test feasibility, not effectiveness, so the program may not actually improve heart health.

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Conditions

The condition(s) this trial relates to.

AIDS cardiovascular disorder HIV infectious disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CARDIOVASCULAR DISEASES HIV

Contacts and locations

Locations

Massachusetts General Hospital
RECRUITING

Boston, Massachusetts, 02114, United States

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