Migraine pill trial pulled before it began
NCT ID NCT05685225
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study planned to test a combination of naltrexone and acetaminophen for treating migraine attacks. It was designed in two stages: first comparing the combo to each drug alone and placebo, then finding the best dose. However, the trial was withdrawn before any participants were enrolled, so no data was collected.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Naltrexone and acetaminophen combination
- What this could lead to
- If it worked, this could offer a new option for treating migraine attacks without opioids.
- What could go wrong
- The trial was withdrawn before enrolling anyone, so no results exist. It is unclear if the combination is safe or effective.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Keystone Clinical Research
North Miami, Florida, 33181, United States
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