Gentler Heart-Lung machine tested in 1,300-Patient trial
NCT ID NCT05487612
First seen Apr 03, 2026
Summary
This study compares a newer, minimally invasive heart-lung machine (MiECC) to the standard machine used during heart surgery. Researchers want to see if the newer machine reduces serious problems like heart attack, stroke, or kidney injury. About 1,300 adults having elective heart surgery will take part.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Cardiothoracic Department AHEPA University Hospital
RECRUITINGThessaloniki, 54636, Greece
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Deparment of Cardiac Surgery, Castle Hill Hospital
ACTIVE_NOT_RECRUITINGHull, HU16 5JQ, United Kingdom
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Department of Cardiac Surgery
ACTIVE_NOT_RECRUITINGCoswig, 06869, Germany
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Department of Cardiac Surgery GVM Anthea Hospital
RECRUITINGBari, 70124, Italy
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Department of Cardiac Surgery GVM Maria Eleonora Hospital
ACTIVE_NOT_RECRUITINGPalermo, 90135, Italy
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Department of Cardiac Surgery, Royal Papworth Hospital
ACTIVE_NOT_RECRUITINGCambridge, CB2 0AY, United Kingdom
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Department of Cardiothoracic Surgery, Hammersmith Hospital
ACTIVE_NOT_RECRUITINGLondon, W120HS, United Kingdom
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Department of Cardiothoracic and Vascular Surgery, Ulm University Hospital
COMPLETEDUlm, 89081, Germany
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Department of Cardiovascular Surgery, Ankara City Hospital
ACTIVE_NOT_RECRUITINGAnkara, Turkey (Türkiye)
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Department of Cardiovascular Surgery, Faculty of Medicine, Recep Tayyip Erdoğan University
RECRUITINGRize, Turkey (Türkiye)
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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Department of Cardiovascular Surgery, Izmir Bakırçay University, Faculty of Medicine
RECRUITINGIzmir, Turkey (Türkiye)
Contact Email: •••••@•••••
Contact Email: •••••@•••••
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Department of Thoracic and Cardiovascular Surgery, University Medical Centre Goettingen
ACTIVE_NOT_RECRUITINGGöttingen, Germany
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Perfusion Services University Health Network, Toronto General Hospital
RECRUITINGToronto, M5G 2C4, Canada
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Email: •••••@•••••
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Minimally invasive extracorporeal circulation (MiECC) device
What this could lead to
If successful, this could show that a newer, gentler heart-lung machine reduces serious complications after heart surgery, leading to better recovery.
What could go wrong
This is an early-stage comparison, not a cure. The device may not prove significantly better than the standard approach, and individual results vary.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.