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Can a blood pressure drug stop deadly fluid buildup in liver failure?

NCT ID NCT07422948

Not yet recruiting Disease control Sponsor: Institute of Liver and Biliary Sciences, India Source: ClinicalTrials.gov ↗

First seen Feb 23, 2026 · Last updated May 15, 2026 · Updated 10 times

Summary

This study tests whether starting midodrine early can better control ascites (fluid buildup in the belly) and prevent kidney complications in people with acute-on-chronic liver failure. About 113 adults with moderate to severe ascites will receive either standard care or standard care plus midodrine. The goal is to see if midodrine helps reduce fluid and avoid the need for large-volume fluid removal procedures.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Institute of Liver and Biliary Sciences

    New Delhi, National Capital Territory of Delhi, 110070, India

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.

ACUTE-ON-CHRONIC LIVER FAILURE