Can a diabetes drug protect blood vessels in type 1 diabetes?
NCT ID NCT05478707
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This phase 2 trial tests whether dulaglutide, a drug used for type 2 diabetes, can improve small blood vessel function in adults with type 1 diabetes. The study involves 47 participants aged 18-40 with long-standing type 1 diabetes. Researchers measure blood flow and insulin sensitivity to see if the drug reduces oxidative stress and improves endothelial health. The trial is currently suspended.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Dulaglutide (a GLP-1 receptor agonist drug, similar to medications used for type 2 diabetes)
What this could lead to
If successful, this could point toward a new way to protect small blood vessels in people with type 1 diabetes, potentially reducing complications like kidney or eye disease.
What could go wrong
This is a small, early-phase trial that is currently suspended. It tests a drug not yet approved for type 1 diabetes, and results may not lead to a new treatment. Risks include side effects from dulaglutide.
Disclaimer
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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University of Virginia
Charlottesville, Virginia, 22908, United States