New drug shows promise for kidney disease in early trial

NCT ID NCT05174221

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This early-stage study tested a drug called mezagitamab in 17 people with IgA nephropathy, a kidney disease. The main goal was to check for side effects and see how the body processes the drug. Participants received injections under the skin for several weeks and were monitored for up to 96 weeks.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • ASST degli Spedali Civili di Brescia - Spedali Civili di Brescia

    Brescia, Lombardy, 25123, Italy

  • Ajou University Hospital

    Suwon, 16499, South Korea

  • Amicis Research Center - Northridge - Nordhoff

    Northridge, California, 91324, United States

  • Beijing Friendship Hospital,Capital Medical University

    Beijing, Beijing Municipality, 100050, China

  • Boise Kidney and Hypertension Institute - Frenova

    Nampa, Idaho, 83687, United States

  • Core Research Group

    Milton, Queensland, 4064, Australia

  • Fujita Health University Hospital

    Toyoake-shi, Aiti, 470-1192, Japan

  • Fundacio Puigvert

    Barcelona, 8025, Spain

  • Guangdong Provincial Peoples Hospital

    Guangzhou, Guangdong, 510080, China

  • Hiroshima University Hospital

    Hiroshima, Hiroshima, 734-8551, Japan

  • Hospital Universitario Marques de Valdecilla

    Santander, Cantabria, 39008, Spain

  • Hospital Universitario Vall d'Hebron - PPDS

    Barcelona, 08035, Spain

  • Hull Royal Infirmary

    Hull, HU3 2JZ, United Kingdom

  • Kasugai Municipal Hospital

    Kasugai-Shi, Aiti, 486-0804, Japan

  • Leicester General Hospital

    Leicester, Leicestershire, LE5 4PW, United Kingdom

  • Monash Health, Monash Medical Centre

    Clayton, Victoria, 3168, Australia

  • National Taiwan University Hospital

    Taipei, 100, Taiwan

  • National University Hospital- Singapore

    Singapore, 119074, Singapore

  • NorthShore University HealthSystem

    Evanston, Illinois, 60201, United States

  • Royal Melbourne Hospital

    Parkville, Victoria, 3050, Australia

  • Sapporo City General Hospital

    Sapporo, Hokkaido, 060-8604, Japan

  • Semmelweis Egyetem

    Budapest, 1083, Hungary

  • Seoul National University Hospital

    Seoul, Seoul Teugbyeolsi, 03080, South Korea

  • Szegedi Tudomanyegyetem Szent-Gyorgyi Albert Klinikai Kozpont

    Szeged, Csongrád megye, 6720, Hungary

  • Taipei Medical University Shuang Ho Hospital

    New Taipei City, 23561, Taiwan

  • The First Affiliated Hospital of Xi'an Jiaotong University

    Xi'an, Shaanxi, 710061, China

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