Steroid trial for COVID brain fog halted early
NCT ID NCT05986422
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tested whether the steroid methylprednisolone could improve memory and thinking in people with long COVID. About 96 adults with ongoing memory problems were to receive either the drug or a placebo for six weeks. The trial was terminated early, so we don't know if the treatment works or is safe.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
methylprednisolone (a steroid that reduces inflammation)
What this could lead to
If it had worked, this could point toward a treatment for memory problems after COVID-19.
What could go wrong
The trial was terminated early, so we don't have clear results. Steroids like methylprednisolone can have side effects, and it's unknown if they help brain fog.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Charité - Universitätsmedizin Berlin
Berlin, State of Berlin, 10117, Germany