One-Dose steroid before liver surgery may cut infections and hospital time
NCT ID NCT07507643
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This phase 3 trial tests whether a single dose of methylprednisolone given before major liver surgery can lower the risk of complications like infections and shorten hospital stays. About 750 adults scheduled for major hepatectomy will be randomly assigned to receive either the steroid or standard care. The study aims to see if this simple addition improves recovery without causing harm.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
methylprednisolone
What this could lead to
If it works, this could lead to fewer infections and shorter hospital stays for patients undergoing major liver surgery.
What could go wrong
This is a single preoperative dose, not a cure. The benefit may be small, and some patients may have adverse reactions to the drug.
Disclaimer
Read more
Show less
This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for HEPATECTOMY are added.
By submitting, you agree to our Terms of use
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
By submitting, you agree to our Terms of use
Study contacts
-
Contact
Phone: •••-•••-•••• Email: •••••@•••••
-
Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
-
Duke University (Data Collection Only)
NOT_YET_RECRUITINGDurham, North Carolina, 27710, United States
Contact Phone: •••-•••-••••
-
Gundersen Lutheran Medical Foundation (Data Collection Only)
NOT_YET_RECRUITINGLa Crosse, Wisconsin, 54601, United States
Contact Phone: •••-•••-••••
-
Henry Ford Hospital (Data collection only)
NOT_YET_RECRUITINGDetroit, Michigan, 48202, United States
Contact Phone: •••-•••-••••
-
Indiana University (Data Collection Only)
NOT_YET_RECRUITINGIndianapolis, Indiana, 46202, United States
Contact Phone: •••-•••-••••
-
Mayo Clinic (Data Collection Only)
NOT_YET_RECRUITINGRochester, Minnesota, 55905, United States
Contact Phone: •••-•••-••••
-
Memoral Sloan Kettering Westchester (Data Collection Only)
RECRUITINGHarrison, New York, 10604, United States
Contact Phone: •••-•••-••••
-
Memorial Sloan Kettering Cancer Center (All Protocol Activities)
RECRUITINGNew York, New York, 10065, United States
Contact Phone: •••-•••-••••
-
Memorial Sloan Kettering Commack (Data Collection Only)
RECRUITINGCommack, New York, 11725, United States
Contact Phone: •••-•••-••••
-
New York University (Data Collection Only)
NOT_YET_RECRUITINGNew York, New York, 10010, United States
Contact Phone: •••-•••-••••
-
Northwell Health (Data collection only)
NOT_YET_RECRUITINGManhasset, New York, 11030, United States
Contact Phone: •••-•••-••••
-
Rush University Medical Center (Data collection only)
NOT_YET_RECRUITINGChicago, Illinois, 606012, United States
Contact Phone: •••-•••-••••
-
Rutgers University (Data Collection Only)
NOT_YET_RECRUITINGNew Brunswick, New Jersey, 08903, United States
Contact Phone: •••-•••-••••
-
SUNY Upstate Medical University
NOT_YET_RECRUITINGSyracuse, New York, 13210, United States
Contact Phone: •••-•••-••••
-
UNIVERSITY OF IOWA (Data Collection Only)
NOT_YET_RECRUITINGIowa City, Iowa, 52242, United States
Contact Phone: •••-•••-••••
-
University of Chicago (Data Collection Only)
NOT_YET_RECRUITINGChicago, Illinois, 60637, United States
Contact Phone: •••-•••-••••
-
University of Kentucky (Data Collection Only)
NOT_YET_RECRUITINGLexington, Kentucky, 40536-0093, United States
Contact Phone: •••-•••-••••
-
University of Nebraska Medical Center (Data Collection Only)
NOT_YET_RECRUITINGOmaha, Nebraska, 68198-7680, United States
Contact Phone: •••-•••-••••
-
University of Wisconsin (Data Collection Only)
NOT_YET_RECRUITINGMadison, Wisconsin, 53792, United States
Contact Phone: •••-•••-••••
-
Washington University (Data Collection Only)
NOT_YET_RECRUITINGSt Louis, Missouri, 63110, United States
Contact Phone: •••-•••-••••