Could a simple numbing drug replace opioids after liver surgery?
NCT ID NCT07590830
First seen May 18, 2026 · Last updated May 18, 2026
Summary
This study looks at whether giving lidocaine (a numbing medicine) through a vein during and after liver surgery can lower the chance of opioid-related side effects like nausea, vomiting, and breathing problems. About 312 adults having planned open liver surgery will be randomly assigned to receive either lidocaine or a placebo (salt water) alongside standard pain care. The goal is to see if lidocaine helps patients recover with fewer side effects and less need for strong painkillers.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Centre 01 - CHU de RENNES, Hôpital Pontchaillou
Rennes, 35000, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Centre 02 - CH Louis Pasteur, Les Hôpitaux de Chartres
Le Coudray, 28630, France
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Centre 03 - CHU de Clermont-Ferrand, Hôpital Estaing
Clermont-Ferrand, 63100, France
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Centre 04 - Centre Hospitalier Départemental de la Vendée
La Roche-sur-Yon, 85000, France
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Centre 05 - CHU de Lille
Lille, 59000, France
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Centre 06 - Centre Léon Bérard
Lyon, 69008, France
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Centre 07 - CHU Nice, Hôpital Archet 2
Nice, 06200, France
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Centre 08 - AP-HP - Sorbonne Université, Hôpital de la Pitié-Salpêtrière
Paris, 75013, France
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Centre 09 - CHU Toulouse, Hôpital Rangueil
Toulouse, 31400, France
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