Could a common diabetes drug help obese nigerians lose weight?

NCT ID NCT07297290

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether metformin, a drug already used for diabetes, can help obese but non-diabetic Black Nigerians lose weight and lower their heart disease risk. Researchers will give 220 participants either metformin or a placebo for several months, tracking changes in weight, waist size, and insulin resistance. The goal is to find an affordable, accessible weight-loss option for a population with limited access to expensive treatments.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Metformin

What this could lead to

If it works, this could provide an affordable, accessible weight-loss option for obese individuals in Nigeria and similar populations.

What could go wrong

This is a single-site trial in a specific population, so results may not apply broadly. Metformin's weight-loss effects are modest, and side effects like gastrointestinal issues are possible.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for INSULIN RESISTANCE are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

Insulin Resistance Obesity obesity disorder Weight Loss

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Pathology Facility

    RECRUITING

    Enugu, Enugu State, Nigeria

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University of Nigeria Teaching Hospital

    RECRUITING

    Enugu, Enugu State, Nigeria

    Contact Phone: •••-•••-•••• Email: •••••@•••••