Common diabetes drug could ease muscle symptoms in rare disease
NCT ID NCT05532813
First seen Jan 10, 2026 · Last updated May 01, 2026 · Updated 16 times
Summary
This study tests whether metformin, a common diabetes medicine, can improve muscle function in people with myotonic dystrophy type 1 (Steinert's disease). The trial will include 142 non-diabetic adults aged 18 to 70 who can still walk. Participants will receive either metformin or a placebo for 6 months, and researchers will measure changes in motor function, strength, breathing, heart health, and quality of life.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Neurology Department, Raymond-Poincaré hospital - APHP
RECRUITINGGarches, 92380, France
Conditions
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