Metformin's Anti-Aging promise put to the test in healthy adults

NCT ID NCT04264897

First seen Apr 24, 2026 · Last updated May 11, 2026 · Updated 2 times

Summary

This study tested whether metformin, a common diabetes drug, can slow aging in healthy adults aged 40 to 75. Researchers gave metformin or a placebo to 101 participants for 12 weeks to see how it affected insulin sensitivity, blood sugar control, and mitochondrial function. The goal was to find out who might benefit from metformin as an anti-aging treatment.

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Contacts and locations

Locations

  • University of Oklahoma Health Sciences Center, Oklahoma Shared Clinical and Translational Resources

    Oklahoma City, Oklahoma, 73104, United States

  • University of Wisconsin-Madison

    Madison, Wisconsin, 53705, United States

Conditions

Explore the condition pages connected to this study.