New MRI dye could spot brain tumors without surgery

NCT ID NCT04772456

First seen Jun 24, 2026 · Last updated Jun 26, 2026 · Updated 2 times

Summary

This study tests a new type of MRI that uses a special substance called hyperpolarized pyruvate to see if it can more accurately diagnose brain tumors (gliomas). Five adults with suspected or known gliomas will receive this injection before a scan, and the results will be compared to standard MRI and tissue samples from surgery or biopsy. The goal is to see if this method is safe and can provide extra information to help diagnose brain cancer.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Hyperpolarized 13C-Pyruvate injection (a special dye for MRI scans)

What this could lead to

If successful, this could lead to a more accurate, non-invasive way to diagnose brain tumors without needing a biopsy.

What could go wrong

This is a very early, small study with only 5 participants, so results may not apply to everyone. The new MRI method may not be more accurate than standard scans.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

glioma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Rosy Njonkou Tchoquessi

    RECRUITING

    Baltimore, Maryland, 21201, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••