New MRI dye could spot brain tumors without surgery

NCT ID NCT04772456

Recruiting now Diagnosis Sponsor: University of Maryland, Baltimore Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 26, 2026 · Updated 2 times

Summary

This study tests a new type of MRI that uses a special substance called hyperpolarized pyruvate to see if it can more accurately diagnose brain tumors (gliomas). Five adults with suspected or known gliomas will receive this injection before a scan, and the results will be compared to standard MRI and tissue samples from surgery or biopsy. The goal is to see if this method is safe and can provide extra information to help diagnose brain cancer.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Hyperpolarized 13C-Pyruvate injection (a special dye for MRI scans)
What this could lead to: If successful, this could lead to a more accurate, non-invasive way to diagnose brain tumors without needing a biopsy.
What could go wrong: This is a very early, small study with only 5 participants, so results may not apply to everyone. The new MRI method may not be more accurate than standard scans.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

glioma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

GLIOMA

Contacts and locations

Locations

Rosy Njonkou Tchoquessi
RECRUITING

Baltimore, Maryland, 21201, United States

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