Ukraine tests combining depression treatment with opioid addiction care

NCT ID NCT05646212

Ongoing Disease control Sponsor: Ukrainian Institute on Public Health Policy Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests different ways to bring mental health treatment into methadone clinics in Ukraine. 1,350 patients from 12 clinics are taking part. Some clinics get extra training and financial rewards to help screen and treat depression. The goal is to see if these strategies improve how many patients get diagnosed, start treatment, and stay on antidepressants.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Selective serotonin reuptake inhibitors (SSRIs) and a telehealth training program (Project ECHO) plus financial incentives for clinics
What this could lead to: If successful, this could show a practical way to treat depression in people receiving opioid addiction treatment, improving their mental health and overall care.
What could go wrong: This is an implementation study, not a test of a new drug. The results may depend on local factors in Ukraine and may not apply elsewhere. The mental health benefits may be modest.

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Conditions

The condition(s) this trial relates to.

Depression depressive disorder opiate dependence

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

DEPRESSION OPIOID-USE DISORDER

Contacts and locations

Locations

Dnipropetrovsk narcological dispensary

Pavlohrad, Dnipropetrovsk Oblast, 51405, Ukraine
Ivano-Frankivsk regional narcological dispensary

Ivano-Frankivsk, 01001, Ukraine
Kropyvnitsky regional narcological dispensary

Kropyvnytskyi, Kirovohrad Oblast, 25000, Ukraine
Kryvyi Rig psycho-neurological dispensary

Kryvyi Rih, Dnipropetrovsk Oblast, 01001, Ukraine
Kyiv city narcological clinic 'Sociotherapia'

Kyiv, 01054, Ukraine
Mykolaiv City Hospital #5

Mykolayiv, 54051, Ukraine
Mykolaiv regional narcological dispensary

Mykolayiv, Mykolaiv Oblast, 54052, Ukraine
Ternopil regional narcological dispensary

Ternopil, Ternopil Oblast, 04050, Ukraine
Vinnitsia regional narcological dispensary 'Sociotherapia'

Vinnytsia, 01001, Ukraine

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