Ukraine tests combining depression treatment with opioid addiction care

NCT ID NCT05646212

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests different ways to bring mental health treatment into methadone clinics in Ukraine. 1,350 patients from 12 clinics are taking part. Some clinics get extra training and financial rewards to help screen and treat depression. The goal is to see if these strategies improve how many patients get diagnosed, start treatment, and stay on antidepressants.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Selective serotonin reuptake inhibitors (SSRIs) and a telehealth training program (Project ECHO) plus financial incentives for clinics

What this could lead to

If successful, this could show a practical way to treat depression in people receiving opioid addiction treatment, improving their mental health and overall care.

What could go wrong

This is an implementation study, not a test of a new drug. The results may depend on local factors in Ukraine and may not apply elsewhere. The mental health benefits may be modest.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Depression depressive disorder opiate dependence

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Dnipropetrovsk narcological dispensary

    Pavlohrad, Dnipropetrovsk Oblast, 51405, Ukraine

  • Ivano-Frankivsk regional narcological dispensary

    Ivano-Frankivsk, 01001, Ukraine

  • Kropyvnitsky regional narcological dispensary

    Kropyvnytskyi, Kirovohrad Oblast, 25000, Ukraine

  • Kryvyi Rig psycho-neurological dispensary

    Kryvyi Rih, Dnipropetrovsk Oblast, 01001, Ukraine

  • Kyiv city narcological clinic 'Sociotherapia'

    Kyiv, 01054, Ukraine

  • Mykolaiv City Hospital #5

    Mykolayiv, 54051, Ukraine

  • Mykolaiv regional narcological dispensary

    Mykolayiv, Mykolaiv Oblast, 54052, Ukraine

  • Ternopil regional narcological dispensary

    Ternopil, Ternopil Oblast, 04050, Ukraine

  • Vinnitsia regional narcological dispensary 'Sociotherapia'

    Vinnytsia, 01001, Ukraine