Scientists probe why menopause raises heart risk

NCT ID NCT06787066

Recruiting now Knowledge-focused Sponsor: University of Missouri-Columbia Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 26, 2026 · Updated 1 time

Summary

This study looks at how the nervous system controls blood flow in women going through menopause. Researchers will measure nerve activity and blood vessel responses in 75 women aged 18-70. They will also test how two drugs (propranolol and phentolamine) affect these responses. The goal is to understand why heart disease risk increases after menopause.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Propranolol Hydrochloride and Phentolamine Injection
What this could lead to: If successful, this study could help explain why women after menopause have higher heart disease risk, potentially leading to better prevention strategies.
What could go wrong: This is a very early, small study (75 participants) focused on understanding mechanisms, not testing a treatment. Results may not apply to all women or lead directly to new therapies.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

MENOPAUSE

Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

University of Missouri
RECRUITING

Columbia, Missouri, 65211, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••

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