Can Omega-3s keep menopausal minds sharp?
NCT ID NCT07814300
First seen Sep 10, 2026 · Last updated Sep 11, 2026 · Updated 1 time
Summary
Researchers are testing whether a daily algae-based omega-3 supplement can improve memory and thinking in perimenopausal and menopausal women aged 40 to 60. The study enrolls 42 women who take either the supplement or a placebo for 12 weeks. Scientists measure changes in verbal and working memory, plus menopausal symptoms, stress, and sleep, to see if omega-3s make a difference.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- an algae-based omega-3 supplement rich in DHA and EPA
- What this could lead to
- If it works, this could offer women a simple daily supplement to help protect memory and ease symptoms during menopause.
- What could go wrong
- This is a small, 12-week study of 42 women, so any memory benefit may be modest or fade. Supplements can also cause stomach upset or a fishy aftertaste.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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42 people
The number who actually took part.
- Started
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Mar 2026
- Expected to finish
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Oct 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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40 to 60 years
- Sex
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Female participants only
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Be female and aged between 40-60 years * Be experiencing perimenopause or menopause * Access to reliable internet connection and a device to complete online questionnaires and cognitive assessments * Be prepared to take a daily omega-3 supplement or placebo for 12 weeks * Be prepared to complete pre- and post- intervention testing and questionnaires * Speak English fluently to confirm they can complete cognitive tests to the best of their ability Exclusion Criteria: * Have diagnosed psychiatric or neurological condition (dementia, extreme depression, schizophrenia, bipolar disorder) which could affect cognitive function * Not currently be taking omega-3 supplements or regularly consuming fatty fish (1 portion per/week) * Be using hormone replacement therapy (HRT) * Have severe dietary restrictions * Have a history of stroke, cardiovascular disease or diabetes, as these conditions influence cognitive health * Are unable to commit to both baseline and follow-up tests after the 12-week period * Pregnant or breastfeeding
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
St Mary's University
London, United Kingdom
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