Real-World data reveals how two drug combos stack up against melanoma

NCT ID NCT07091695

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This completed study looked at 100 adults with stage III melanoma that could be removed by surgery. Researchers compared two immunotherapy drug combinations given before surgery: nivolumab plus relatlimab versus nivolumab plus ipilimumab. The goal was to understand patient characteristics, treatment patterns, and outcomes like survival and tumor response in real-world settings.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Nivolumab + relatlimab or nivolumab + ipilimumab (immunotherapy drugs)

What this could lead to

If successful, this could help doctors understand which drug combination works better for melanoma patients before surgery, potentially improving treatment decisions.

What could go wrong

This is an observational study, not a controlled trial, so results may be influenced by factors other than the drugs. It also only looks back at past data, so it cannot prove cause and effect.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

cutaneous melanoma melanoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Cardinal Health

    Dublin, Ohio, 43017, United States