New hope for advanced melanoma: experimental drug shows promise in early trial

NCT ID NCT05419388

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested two different doses of an experimental drug called RO7247669 in 93 people with advanced melanoma that had not been treated before. The goal was to see how well the drug controls the cancer and to find the best dose with the fewest side effects. Participants received the drug by infusion, and researchers measured how long the cancer stayed under control and how many people had their tumors shrink.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

melanoma metastatic melanoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Adana Baskent University Hospital

    Adana, 01120, Turkey (Türkiye)

  • Auckland City Hospital, Cancer and Blood Research

    Auckland, 1023, New Zealand

  • Coffs Harbour Health Campus

    Coffs Harbour, New South Wales, 2450, Australia

  • District General Hospital of Athens Laiko

    Athens, 115 27, Greece

  • Hospital Clínic i Provincial

    Barcelona, 08036, Spain

  • Hospital Sírio-Libanês

    São Paulo, São Paulo, 01308-050, Brazil

  • Hospital Universitari Vall d'Hebron

    Barcelona, 08035, Spain

  • Hospital de Cancer de Barretos

    Barretos, São Paulo, 14784-400, Brazil

  • Hospital de Clínicas de Porto Alegre X

    Porto Alegre, Rio Grande do Sul, DUMMY_VALUE, Brazil

  • Instituto do Cancer do Estado de Sao Paulo - ICESP

    São Paulo, São Paulo, 01246-000, Brazil

  • Medipol Mega Üniversite Hastanesi Göztepe

    Istanbul, 34214, Turkey (Türkiye)

  • Melanoma Institute Australia

    North Sydney, New South Wales, 2060, Australia

  • Memorial Ankara Hastanesi

    Ankara, 06520, Turkey (Türkiye)

  • Narodny Onkologicky Ustav

    Bratislava, 833 10, Slovakia

  • Narodowy Instytut Onkologii im. M.Sklodowskiej-Curie

    Warsaw, 02-781, Poland

  • One Clinical Research

    Nedlands, Western Australia, 6009, Australia

  • POKO Poprad

    Poprad, 058 01, Slovakia

  • Princess Alexandra Hospital

    Woolloongabba, Queensland, 4102, Australia

  • Princess Margaret Cancer Centre

    Toronto, Ontario, M5G 2M9, Canada

  • Uniwersyteckie Centrum Kliniczne

    Gda?sk, 80-214, Poland

  • Všeobecná fakultní nemocnice v Praze

    Prague, 128 08, Czechia

  • Wellington Hospital

    Wellington, 6002, New Zealand