Oxygen levels in melanoma may predict cancer spread

NCT ID NCT06831071

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study is investigating whether low oxygen levels (hypoxia) in melanoma tumors and nearby lymph nodes are linked to worse outcomes. Researchers will give 50 patients a safe oral tracer called pimonidazole before their standard surgery. By measuring hypoxia in the removed tissue, they hope to better understand how melanoma spreads and improve future treatment decisions.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
Pimonidazole
What this could lead to
If successful, this could help doctors better predict which melanomas are more likely to spread, guiding more personalized treatment.
What could go wrong
This is a small, early-stage observational study, not a treatment trial. The findings may not lead to immediate changes in patient care.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • UPMC Hillman Cancer Center

    RECRUITING

    Pittsburgh, Pennsylvania, 15232, United States

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Other studies related to the condition(s) this trial covers.