Scientists test gene injection to turn tumors against themselves

NCT ID NCT01397708

Summary

This early-stage study tested a new two-part treatment for advanced melanoma that cannot be surgically removed. The treatment involved injecting a modified virus directly into tumors to deliver a gene that may help the immune system fight cancer, combined with an oral pill to activate it. The main goal was to check the safety and side effects of this approach in a small group of 26 patients.

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Contacts and locations

Locations

  • Atlantic Melanoma Center

    Morristown, New Jersey, 07960, United States

  • Fletcher Allen Health

    Burlington, Vermont, 05401, United States

  • Indiana University Health Goshen Center for Cancer Care

    Goshen, Indiana, 46526, United States

  • James Graham Brown Cancer Center

    Louisville, Kentucky, 40202, United States

  • Mary Crowley Cancer Research Center

    Dallas, Texas, 75201, United States

  • Oncology Specialists

    Park Ridge, Illinois, 60068, United States

  • St. Lukes

    Easton, Pennsylvania, 15232, United States

  • The Angeles Clinic

    Los Angeles, California, 90404, United States

  • Washington University

    St Louis, Missouri, 63110, United States

Conditions

Explore the condition pages connected to this study.