Medical cannabis vouchers may cut opioid use in chronic pain patients

NCT ID NCT04495725

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested whether giving adults with chronic pain discounted vouchers for medical cannabis soft-gel capsules could help them reduce their opioid painkiller use. 270 participants were randomly assigned to receive vouchers for placebo or cannabis capsules with different THC-to-CBD ratios. The main goal was to see if the vouchers led to lower total opioid doses over the study period.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

medical cannabis soft-gel capsules (various THC:CBD ratios)

What this could lead to

If successful, this could show that providing discounted medical cannabis helps people with chronic pain lower their opioid use, potentially reducing opioid-related harms.

What could go wrong

This is a completed trial with 270 participants, but results may not apply to all pain types or cannabis products. The use of vouchers may not reflect real-world access or long-term effects.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

cannabis dependence Chronic Pain chronic pain syndrome opioid abuse Pain

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Vireo Health of New York

    Queens, New York, 11373, United States