Medical cannabis vouchers may cut opioid use in chronic pain patients

NCT ID NCT04495725

Completed Disease control Sponsor: Vireo Health Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested whether giving adults with chronic pain discounted vouchers for medical cannabis soft-gel capsules could help them reduce their opioid painkiller use. 270 participants were randomly assigned to receive vouchers for placebo or cannabis capsules with different THC-to-CBD ratios. The main goal was to see if the vouchers led to lower total opioid doses over the study period.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: medical cannabis soft-gel capsules (various THC:CBD ratios)
What this could lead to: If successful, this could show that providing discounted medical cannabis helps people with chronic pain lower their opioid use, potentially reducing opioid-related harms.
What could go wrong: This is a completed trial with 270 participants, but results may not apply to all pain types or cannabis products. The use of vouchers may not reflect real-world access or long-term effects.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

cannabis dependence Chronic Pain chronic pain syndrome opioid abuse Pain

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CHRONIC PAIN MARIJUANA OPIOID USE

Contacts and locations

Locations

Vireo Health of New York

Queens, New York, 11373, United States

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