AI doctors in training: can a computer learn to diagnose stomach and heart diseases?
NCT ID NCT07795645
First seen Aug 31, 2026 · Last updated Sep 01, 2026 · Updated 1 time
Summary
This study aims to develop and fine-tune a medical artificial intelligence (AI) model to assist with diagnosing and managing gastric, cardiovascular, and cerebrovascular diseases. Researchers will use a large dataset of patient records, medical images, and doctor-patient dialogues from three hospitals to train the model. The goal is to create a tool that can support doctors in making more accurate and efficient decisions, potentially improving care for conditions like chronic gastritis, gastric cancer, coronary artery disease, and stroke.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- A medical artificial intelligence (AI) model, fine-tuned on patient data to assist with diagnosis and treatment planning for gastric, cardiovascular, and cerebrovascular diseases.
- What this could lead to
- If successful, this could lead to AI tools that help doctors diagnose and treat stomach, heart, and brain diseases more accurately and efficiently, potentially improving patient care.
- What could go wrong
- This is an observational study focused on developing and validating the AI model, not on treating patients directly. The model may not perform well in real-world settings or across different hospitals, and there are risks of bias in the data.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 96,000 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Nov 2024
- Expected to finish
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Aug 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
The study population consists of patients diagnosed with chronic gastritis, gastric cancer, coronary artery disease, or stroke, enrolled from three hospitals in Beijing: Beijing Friendship Hospital, Beijing Anzhen Hospital, and Beijing Xuanwu Hospital. The study includes approximately 80,000 retrospective historical medical records and approximately 16,000 prospectively enrolled patients. All participants are aged 18 years or older.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Retrospective Historical Medical Records: patients with stomach, cardiovascular and cerebrovascular diseases from September 2014 to August 2024 were enrolled. (1) Age ≥ 18 years; (2) Diagnosed with any of the following: chronic gastritis, gastric cancer, gastro esophageal reflux, coronary artery disease, or stroke. * Prospective Historical Medical Records: Patients with stomach, cardiovascular and cerebrovascular diseases from September 2024 and August 2027 are enrolled.Outpatient and emergency records are used for large model training, and inpatient records are used for both training and internal validation. Inpatient records are allocated to the training set and internal validation set at a 3:1 ratio. Block randomization is used to reduce bias. Each sample is assigned a raw random number uniformly distributed between 0 and 1. Under the block design, each block contains 4 samples. Within each block, samples are ranked by the raw random number and assigned a random code from 1 to 4. The randomization schedule is prepared by a statistician on a computer system before the start of the study and printed on opaque, sealed envelopes. 1. Age ≥ 18 years; (2) Clinically diagnosed with one of the following: chronic gastritis, gastric cancer, gastro esophageal reflux, coronary artery disease, or stroke; (3) Patient or legally authorized representative able to understand the study and provide informed consent; (4) Clinically stable and able to complete the study procedures Exclusion Criteria: * Retrospective Historical Medical Records: (1) Records with information that cannot be correctly read due to modification or smudging; (2) Examination reports that are smudged or damaged, making them uninterpretable by the large model. * Prospective Historical Medical Records: (1) Severe psychiatric disorders (e.g., depression, mania, epilepsy, schizophrenia); (2) Judged by the investigator to be unable to comply with study procedures; (3) Poor audio quality due to accent or recording issues that prevents accurate data capture; (4) Laboratory or imaging reports that are smudged or damaged, making them uninterpretable by the model * Withdrawal Criteria: Prospective Historical Medical Records: 1. Participant requests to withdraw from the study during the research process 2. Investigator determines that the study should be terminated based on consideration of the participant's best interests
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Beijing Friendship Hospital, Capital Medical University
RECRUITINGBeijing, China
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