Could a simple antibiotic cocktail slash infection risk in colon cancer surgery?
NCT ID NCT07429760
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study compares two ways of preparing the bowel before left-sided colorectal cancer surgery: standard mechanical bowel prep alone versus mechanical prep plus oral antibiotics (rifaximin and metronidazole). The goal is to see if adding antibiotics reduces surgical site infections within 30 days. Sixty adults scheduled for curative surgery are being enrolled.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Rifampicin (also called Metronidazole) and Rifaximin
What this could lead to
If it works, this could show that adding oral antibiotics to standard bowel prep lowers the risk of surgical site infections after colorectal cancer surgery.
What could go wrong
This is a small, early-stage trial with only 60 participants, so results may not apply to all patients. The antibiotics may cause side effects or not reduce infections as hoped.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Shaukat Khanam Memorial Cancer Hospital & Research Centre Lahore
Lahore, Punjab Province, Pakistan