New drug shows promise against rare salivary gland cancer

NCT ID NCT03781986

First seen Jun 27, 2026 · Last updated Jul 14, 2026 · Updated 2 times

Summary

This study tests a new drug called APG-115, alone or with chemotherapy, in people with a certain type of salivary gland cancer that has a normal p53 gene. The goal is to see if the drug can shrink tumors and to find the best dose with acceptable side effects. About 41 adults with advanced cancer that cannot be cured will take part.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Moffitt Cancer Center

    Tampa, Florida, 33612, United States

  • University of Chicago

    Chicago, Illinois, 60637, United States

  • University of Michigan Rogel Cancer Center

    Ann Arbor, Michigan, 48109, United States

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