New drug MCAM takes first step toward fighting opioid addiction

NCT ID NCT07602335

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This early-phase trial will test the safety and blood levels of an investigational drug called MCAM in 24 healthy adults. Participants will receive a single dose of MCAM or a placebo and be monitored for 8 days. The goal is to find the highest safe dose for future studies on opioid use disorder.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

MCAM (an investigational drug taken by mouth)

What this could lead to

If this early safety trial succeeds, it could pave the way for a new medication to help control opioid use disorder.

What could go wrong

This is a very early Phase 1 trial with only 24 healthy participants, so it is not designed to test effectiveness. The drug may cause side effects or fail to show benefit in later studies.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

opiate dependence

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Dr. Vince Clinical Research

    Overland Park, Kansas, 66212, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••