New pill for ulcerative colitis passes first safety check in healthy volunteers
NCT ID NCT06363383
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This early-stage trial tested whether an oral biologic drug called MB-001 is safe in 48 healthy adults. Participants received either a single dose or five daily doses of the drug or a placebo. The main goal was to check for side effects and see how the body processes the drug. This is a first step toward possibly treating ulcerative colitis.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- MB-001 (an oral biologic drug)
- What this could lead to
- If safe, this could lead to larger trials testing whether MB-001 helps control ulcerative colitis symptoms.
- What could go wrong
- This is a very early Phase 1 safety study in healthy people, not patients. It is too soon to know if MB-001 will work for ulcerative colitis.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
CMAX
Adelaide, South Australia, 5000, Australia
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Other studies related to the condition(s) this trial covers.
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