Can a common painkiller combo stop Post-Surgery confusion in seniors?
NCT ID NCT05834569
First seen Jun 26, 2026 · Last updated Jun 26, 2026 · Updated 1 time
Summary
This study looked at whether giving elderly patients a combination of acetaminophen and ibuprofen (Maxigesic) during and after minimally invasive lung surgery could reduce the risk of postoperative delirium (sudden confusion). The trial planned to compare the drug group to a placebo group, but it was terminated early and only enrolled 25 people. Because of this, the results are not strong enough to draw clear conclusions.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Maxigesic (acetaminophen and ibuprofen combination)
What this could lead to
If it worked, this could point toward a simple way to lower the risk of confusion after lung surgery in older adults.
What could go wrong
The trial was terminated early and very small (25 people), so results are limited. It's unclear if the drug truly helps, and risks include allergic reactions or bleeding.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Korea University Guro Hospital
Seoul, 08308, South Korea