Parent coaching may rewire kids' brains to fight depression

NCT ID NCT06725160

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether teaching mothers with depression to encourage positive emotions in their young children (ages 4-6) can increase the child's brain response to rewards. 180 mother-child pairs will be randomly assigned to either a parent-coaching program or general parenting support. Brain activity is measured before and after using EEG.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Parent coaching (behavioral intervention)

What this could lead to

If successful, this could point toward a simple parenting strategy to strengthen children's brain reward systems, potentially reducing future depression risk.

What could go wrong

This is a small, early mechanistic study (180 participants) looking at brain signals, not clinical outcomes. The coaching is brief (3 sessions) and may not produce lasting changes.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for DEPRESSION are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

Behavior Depression depressive disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • University of Pittsburgh

    RECRUITING

    Pittsburgh, Pennsylvania, 15213, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••