Scientists study mast cells to unlock mastocytosis mysteries

NCT ID NCT00044122

Recruiting now Knowledge-focused Sponsor: National Institute of Allergy and Infectious Diseases (NIAID) Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jul 16, 2026 · Updated 7 times

Summary

This study collects bone marrow and blood samples from up to 600 people with mastocytosis, a condition where too many mast cells cause symptoms like itching and bone pain. Researchers will study what makes these cells grow and survive. The goal is to learn more about the disease, not to test a new treatment.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If this research succeeds, it could point toward new treatments that control mast cell growth in mastocytosis.
What could go wrong: This is an observational study, not a treatment trial. It is early-stage research that may not directly lead to therapies.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

bone marrow disorder mastocytosis monoclonal gammopathy

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

BONE MARROW MASTOCYTOSIS MONOCLONAL TRYPTASE

Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••
Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

National Institutes of Health Clinical Center
RECRUITING

Bethesda, Maryland, 20892, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••

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