Can a bone marrow injection save young hips after fracture?

NCT ID NCT07808294

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Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
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Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Sep 08, 2026 · Last updated Sep 09, 2026 · Updated 1 time

Summary

This trial tests whether injecting a person's own bone marrow into a hip fracture site helps the bone heal faster and more completely. Adults aged 18 to 55 with a specific type of hip fracture will receive either standard screw fixation alone or screw fixation plus a bone marrow injection. The study tracks fracture healing time, rates of nonunion, and the development of avascular necrosis, a condition where the bone's blood supply fails. The goal is to find a way to preserve the natural hip joint and avoid the need for a hip replacement in younger patients.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Autologous bone marrow injected at the fracture site during screw fixation surgery
What this could lead to
If it works, this approach could help younger adults with hip fractures heal faster and avoid the need for a hip replacement later in life.
What could go wrong
The trial is small and early, so results may not apply broadly. Bone marrow injection carries risks like infection or bleeding, and it may not prevent bone death or nonunion.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 32 people

The number the study aims to enrol. It can still change while the study runs.

Started

May 2025

Expected to finish

Aug 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 55 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age between 18 and 55 years. * Intracapsular femoral neck fracture classified as Garden type III or IV. * The time elapsed since the fracture occurred must not exceed 24 hours Exclusion Criteria: * Age under 18 years or over 55 years. * Open femoral neck fracture. * Neglected femoral neck fractures or fractures that occurred more than 24 hours prior to presentation. * Polytrauma patients who are in shock or admitted to the intensive care unit (ICU).

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

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  3. A doctor treating you

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Contacts and locations

Locations

  • Idlib university Faculty of medicine

    RECRUITING

    Idlib, Syria

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