New depression pill shows promise in Drug-Resistant patients

NCT ID NCT03870776

Completed Symptom relief Sponsor: Mapreg Source: ClinicalTrials.gov ↗

First seen Apr 01, 2026 · Last updated May 08, 2026 · Updated 5 times

Summary

This study tested an experimental daily pill called MAP4343 in 126 adults whose depression did not improve with standard antidepressants. Participants took the drug or a placebo for 6 weeks, and researchers measured changes in depression symptoms using a standard rating scale. The goal was to see if MAP4343 could help people who have not responded to other treatments.

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Contacts and locations

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Locations

APHP Hôpital La Pitié Salpétrière - Prinicipal investigator center

Paris, 75013, France
CHD Vendée

La Roche-sur-Yon, 85000, France
CHRU Tours

Tours, 37000, France
CHU Angers

Angers, 49900, France
CHU Besançon

Besançon, 25000, France
CHU Henri Laborit

Poitiers, 86000, France
CHU Nantes

Nantes, 44000, France
Cabinet Médical Ambroise Paré

Élancourt, 78990, France
Hôpital Fontan 1

Lille, 59000, France
Hôpital Ste Anne

Paris, 75014, France

Conditions

Explore the condition pages connected to this study.

DEPRESSION