Healthy volunteers bitten by mosquitoes in malaria experiment
NCT ID NCT06607003
First seen Jun 26, 2026 · Last updated Jul 01, 2026 · Updated 4 times
Summary
This study gives healthy adults a controlled malaria infection using donated blood containing the P. vivax parasite. Researchers will monitor how the infection develops, how the immune system responds, and whether mosquitoes can pick up the parasite from participants. The goal is to create a safe model for testing future vaccines and treatments. Participants will take chloroquine to clear the infection and will have follow-up visits for three weeks.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
P. vivax malaria parasite in donated blood
What this could lead to
If successful, this could provide a safe model to test future malaria vaccines and treatments, and help understand how the parasite spreads.
What could go wrong
This is an early-phase study with only 300 participants, focused on observation, not treatment. Participants will get malaria symptoms and must stay in the clinic for several days.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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National Institutes of Health Clinical Center
RECRUITINGBethesda, Maryland, 20892, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••