Mailed cancer tests battle: which stool test screens better for colon cancer?

NCT ID NCT06931860

First seen Jun 24, 2026 · Last updated Jun 26, 2026 · Updated 1 time

Summary

This study compares two mailed stool tests—Cologuard and FIT—for colorectal cancer screening in adults aged 45-49 who are not up to date with screening. Researchers will measure how many people complete screening and follow up on abnormal results. The goal is to find the most effective way to detect colorectal cancer early in this age group.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Cologuard (multi-target stool DNA test) and FIT (fecal immunochemical test)
What this could lead to
If this trial succeeds, it could show which mailed stool test works better for screening younger adults, potentially increasing early detection of colorectal cancer.
What could go wrong
This is a small, early-stage study (400 participants) comparing two existing tests, not a new treatment. Results may not apply to broader populations or different healthcare settings.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • University of California San Diego

    La Jolla, California, 92093, United States

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