New drug combo shows promise for tough childhood cancers
NCT ID NCT04751383
First seen Feb 01, 2026 · Last updated Jun 06, 2026 · Updated 15 times
Summary
This early-stage trial tested a combination of two drugs, magrolimab and dinutuximab, in 12 children and young adults with neuroblastoma or osteosarcoma that had come back or stopped responding to treatment. The main goal was to find the safest dose and see if the combination could shrink or stabilize tumors. Researchers also looked at side effects and how the body processed the drugs.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Baylor College of Medicine/Dan L Duncan Comprehensive Cancer Center
Houston, Texas, 77030, United States
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British Columbia Children's Hospital
Vancouver, British Columbia, V6H 3V4, Canada
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Children's Hospital Colorado
Aurora, Colorado, 80045, United States
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Children's Hospital Los Angeles
Los Angeles, California, 90027, United States
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Children's Hospital of Philadelphia
Philadelphia, Pennsylvania, 19104, United States
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Dana-Farber Cancer Institute
Boston, Massachusetts, 02215, United States
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Hospital for Sick Children
Toronto, Ontario, M5G 1X8, Canada
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Lucile Packard Children's Hospital Stanford University
Palo Alto, California, 94304, United States
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Seattle Children's Hospital
Seattle, Washington, 98105, United States
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UCSF Medical Center-Mission Bay
San Francisco, California, 94158, United States
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University of Chicago Comprehensive Cancer Center
Chicago, Illinois, 60637, United States
Conditions
Explore the condition pages connected to this study.