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Could magnesium be the key to better sleep and less pain in lipedema?

NCT ID NCT07779577

Knowledge-focused Sponsor: Fatih Sultan Mehmet Training and Research Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Aug 21, 2026 · Last updated Aug 21, 2026

Summary

This study looks at whether magnesium levels in the blood are related to sleep quality, pain, and quality of life in women with lipedema, a condition that causes abnormal fat buildup in the legs. Researchers will compare women with good sleep versus poor sleep to see if magnesium levels differ. The goal is to better understand these connections, which could inform future care.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
serum magnesium level (observational measurement)
What this could lead to
If a link is found, it could point toward magnesium as a factor in managing sleep and pain for lipedema patients.
What could go wrong
This is an observational study, so it cannot prove cause and effect. Results may be influenced by other factors and may not apply to all patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 128 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Aug 2026

An estimate. Start dates often move.

Expected to finish

Sep 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Patients with lipedema who are 18 years of age or older

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Serum magnesium levels must have been measured within the past 6 month * Be at least 18 years of age * Have a diagnosis of lipedema based on the Wold criteria * Have no cognitive or mental health issues * Agree to participate in the study Exclusion Criteria: * No serum magnesium level measured within the past 6 months * Use of magnesium supplements for lipedema within the past 6 months, or the presence of any condition known to affect magnesium absorption or serum magnesium levels (e.g., use of a proton pump inhibitor \[PPI\] or diuretic) * The presence of other types of edema in which a component other than lipedema is predominant (e.g., lymphedema, venous edema, edema associated with heart or kidney failure, etc.) * A body mass index (BMI) of over 50.0 (this condition reflects severe obesity, which has a significant impact on health beyond lipedema alone) * Presence of a rheumatological disease, history of cancer, chronic liver disease, or endocrine disorder * Having been diagnosed with a psychiatric disorder, or use of psychiatric medications that may affect sleep * Being under 18 years of age

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Conditions

The condition(s) this trial relates to.

Lipedema magnesium deficiency

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Lipedema Magnesium

How to take part

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  1. The official record

    The full official record for this study. This one lists no contact details, but it is the first place any would appear.

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