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Can a Self-Drainage routine match Therapist-Led care for lipedema?

NCT ID NCT07803926

Symptom relief Sponsor: Merve SEVINC GUNDUZ Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Sep 04, 2026 · Last updated Sep 04, 2026

Summary

This trial tests two six-week physiotherapy programs in women with lipedema, a condition that causes painful fat buildup in the legs. One group receives manual lymphatic drainage from a therapist plus supervised aerobic exercise. The other group learns self-lymphatic drainage and gets physical activity guidance. Researchers will compare the effects on pain, leg function, limb size, mobility, quality of life, and mood.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Manual lymphatic drainage, aerobic exercise, self-lymphatic drainage, and physical activity guidance
What this could lead to
If one approach proves better, it could point to a more effective standard physiotherapy program for easing pain and improving mobility in women with lipedema.
What could go wrong
The trial is small and early, so results may not apply to all women with lipedema. The benefits may be modest, and the study does not test long-term effects.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 34 people

The number the study aims to enrol. It can still change while the study runs.

Started

Aug 2026

Expected to finish

Jan 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 65 years

Sex

Female participants only

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: Female sex. Aged 18 to 65 years. Diagnosed with lipedema. Diagnosed with Stage I, II, III, or IV lipedema. No participation in any physiotherapy program within the previous 3 months. No previous liposuction surgery. Not currently following a weight-loss diet. No change in body weight greater than 10% within the previous 6 months. Willing to participate in the study and provide informed consent. Exclusion Criteria: Severe visual or cognitive impairment. Severe cardiovascular disease. Musculoskeletal conditions or injuries affecting the lower extremities, including osteoarthritis, contracture, or osteoporosis, that may interfere with participation in the study. Skin conditions that may interfere with the intervention, such as pressure ulcers. Uncontrolled endocrine disorders, including type 1 or type 2 diabetes mellitus or hypothyroidism. Obesity secondary to endocrine disorders or medication-induced obesity. Use of estrogen-progestin therapy within the previous 2 months. Pregnancy or a positive pregnancy test. Breastfeeding. Concurrent participation in another clinical trial.

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Conditions

The condition(s) this trial relates to.

Lipedema Motor Activity Pain

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Lipedema

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The study's own enquiry address

    This study publishes an address for enquiries. See it below .

  2. The places running it

    1 site. The list below names each one and where it is.

  3. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  4. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Bezmialem Vakif University

    RECRUITING

    Istanbul, Eyupsultan, Turkey (Türkiye)

    Contact Email: •••••@•••••

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