Balloon vs. stent: new hope for tiny heart arteries?
NCT ID NCT06271590
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This trial tests a special balloon coated with sirolimus (a drug) to treat small arteries in the heart, compared to standard drug-eluting stents. About 1605 people with coronary artery disease will be randomly assigned to one of the two treatments. The goal is to see if the balloon is as safe and effective as stents for keeping these small vessels open.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Sirolimus-coated balloon (MagicTouch)
What this could lead to
If successful, this could offer a stent-free option for treating small heart arteries, potentially reducing long-term complications.
What could go wrong
This is a large trial but still early for this device in small vessels. It may not prove superior or even non-inferior to stents, and risks like vessel injury or need for repeat procedures remain.
Disclaimer
Read more
Show less
This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for CARDIOVASCULAR DISEASES are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
By submitting, you agree to our Terms of use
Study contacts
-
Contact
Phone: •••-•••-•••• Email: •••••@•••••
-
Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
-
Atlanta VA Medical Center
NOT_YET_RECRUITINGDecatur, Georgia, 30033, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
-
Atlanticare Regional Medical Center
RECRUITINGPomona, New Jersey, 08401, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
-
Baylor Scott & White The Heart Hospital - Plano
RECRUITINGPlano, Texas, 75093, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
-
Cedars-Sinai Medical Center
NOT_YET_RECRUITINGLos Angeles, California, 90048, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
-
Clearwater Cardiovascular and Interventional Consultants
RECRUITINGClearwater, Florida, 33756, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
-
Cleveland Clinic
NOT_YET_RECRUITINGCleveland, Ohio, 44195, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
-
Columbia University/NYP
NOT_YET_RECRUITINGNew York, New York, 10032, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
-
Dignity Health - Mercy Gilbert Medical Center
NOT_YET_RECRUITINGGilbert, Arizona, 85297, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
-
Emory University Hospital /Emory School of Medice
NOT_YET_RECRUITINGAtlanta, Georgia, 30322, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
-
Icahn School of Medicine at Mount Sinai/ Mount Sinai Hospital
RECRUITINGNew York, New York, 10029, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
-
Loyola University Medical Center
NOT_YET_RECRUITINGMaywood, Illinois, 60153, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
-
Montefiore Medical Center
RECRUITINGThe Bronx, New York, 10467, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
-
NC Heart and Vascular Research, LLC
NOT_YET_RECRUITINGRaleigh, North Carolina, 27607, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
-
North Mississippi Medical Center
NOT_YET_RECRUITINGTupelo, Mississippi, 38801, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
-
North Shore University Hospital - Northwell
NOT_YET_RECRUITINGManhasset, New York, 11030, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
-
Providence St. Vincent Medical Center
NOT_YET_RECRUITINGPortland, Oregon, 97225, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
-
Tallahassee Research Institute
NOT_YET_RECRUITINGTallahassee, Florida, 32308, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
-
Tampa General Hospital / University of South Florida
NOT_YET_RECRUITINGTampa, Florida, 33606, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
-
University Hospitals, Cleveland Medical Center
NOT_YET_RECRUITINGBrooklyn, New York, 11215, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
-
University Hospitals, Cleveland Medical Center
NOT_YET_RECRUITINGCleveland, Ohio, 44106, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
-
University of Florida Health Sciences Center-Jacksonville
NOT_YET_RECRUITINGJacksonville, Florida, 32209, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
-
University of Oklahoma Health Science Center
NOT_YET_RECRUITINGOklahoma City, Oklahoma, 73104, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
-
University of Pittsburgh Medical center (UPMC)
NOT_YET_RECRUITINGPittsburgh, Pennsylvania, 15123, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
-
West Virginia University Heart & Vascular Institute
NOT_YET_RECRUITINGMorgantown, West Virginia, 26506, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••