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Which nerve block wins the battle against Post-Surgery pain?

NCT ID NCT06810206

Symptom relief Sponsor: Kasr El Aini Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Aug 20, 2026 · Last updated Aug 21, 2026 · Updated 1 time

Summary

This trial compares two ultrasound-guided nerve blocks—M-TAPA and EOIPB—to see which provides better pain relief after laparoscopic gallbladder removal. Sixty adults scheduled for this surgery will be randomly assigned to receive one of the two blocks. The study measures pain scores over 24 hours and recovery quality, aiming to reduce opioid use and improve patient comfort.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Two regional anesthesia techniques: modified thoracoabdominal plane block (M-TAPA) and external oblique intercostal plane block (EOIPB), both guided by ultrasound.
What this could lead to
If one block proves better, it could become the standard for managing pain after laparoscopic gallbladder surgery, reducing opioid needs and speeding recovery.
What could go wrong
This is a small, early-stage comparison, so results may not apply broadly. Nerve blocks carry risks like infection, bleeding, or incomplete pain relief.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 60 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Nov 2026

An estimate. Start dates often move.

Expected to finish

Nov 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 65 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Adults aged 18-65 years * Scheduled for Laparoscopic cholecystectomy surgery * ASA (American Society of Anaesthesiologists) physical status I-II Exclusion Criteria: * Known allergy to local anaesthetics * Coagulopathy or anticoagulant use * Infection at the site of block * Chronic pain conditions * Advanced liver or kidney failure * History of abdominal surgery or trauma * Alcohol or drug use * Refusal to participate * Chronic opioid consumption * Use of painkillers in the preoperative 24hours * Conversion to open surgery * Body mass index ( BMI ) \> 35

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Conditions

The condition(s) this trial relates to.

Pain, Postoperative

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Post operative pain

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Faculity of medicine , Kasr Al Aini Hospitals , Cairo University

    Cairo, Egypt

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