Cure My Disease

Don't miss your cure!

 Log in / Sign up

Can a better cleaning method ease root canal pain?

NCT ID NCT07788027

Symptom relief Sponsor: Minia University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Aug 26, 2026 · Last updated Aug 27, 2026 · Updated 1 time

Summary

This trial tests whether different ways of delivering and activating a cleaning solution during root canal treatment can reduce pain afterward. It includes adults aged 18 to 45 who need a first root canal on a canine or premolar tooth with an oval-shaped canal. Participants are randomly assigned to one of four irrigation methods, and they rate their pain at several time points over a week. The goal is to see which method leads to the least discomfort after the procedure.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Sodium hypochlorite 5.25% used with different irrigation and activation methods (manual agitation, conventional needle, sonic activation, and negative pressure systems)
What this could lead to
If successful, this could identify the best irrigation method to reduce pain after root canal treatment, improving patient comfort.
What could go wrong
This is a small, early-stage trial, so results may not apply to all patients. Pain is subjective and can vary widely, and the different methods may show no clear advantage.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 32 people

The number the study aims to enrol. It can still change while the study runs.

Started

Apr 2026

Expected to finish

Apr 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 45 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Inclusion Criteria Patients aged between 18 and 45 years. * Patients requiring primary root canal treatment. * Patients in good general health.. * Subjects classified as ASA-1 following the classification proposed by the American Society of Anesthesiologists. Exclusion Criteria: * Patients with systemic diseases affecting pain perception or healing. * Patients who had taken analgesics or antibiotics within 12-24 hours prior to treatment. * Pregnant or lactating women. * Previously treated teeth or teeth with root resorption, fractures, or severe periodontal disease. .

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for Post operative pain are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

Pain, Postoperative

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Post operative pain

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Endodontics Department Faculty of Dentistry

    RECRUITING

    Minya, Egypt

More trials for these conditions

Other studies related to the condition(s) this trial covers.