At-Home swab could spot uterine cancer in lynch syndrome patients

NCT ID NCT07194551

First seen Sep 30, 2025 · Last updated Jun 21, 2026 · Updated 41 times

Summary

This study tests whether people with Lynch syndrome can use a self-collected vaginal swab at home to detect early signs of uterine cancer. Researchers will check if participants find the process easy and acceptable, and whether DNA from the swab can predict cancer risk. The goal is to develop a less invasive screening option for this high-risk group.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-••••

Locations

  • VGH Research Pavilion

    RECRUITING

    Vancouver, British Columbia, V5Z 1M9, Canada

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

vaginal swab and pH test kit

What this could lead to

If successful, this could offer a simple, at-home screening method to catch uterine cancer early in people with Lynch syndrome.

What could go wrong

This is a small, early feasibility study with only 30 participants, so results may not apply to everyone. The test may not accurately predict cancer risk.

Conditions

The condition(s) this trial relates to.

Colorectal Neoplasms, Hereditary Nonpolyposis endometrium neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.