Could a celery compound help schizophrenia?

NCT ID NCT05204407

Completed Symptom relief Sponsor: University of Maryland, Baltimore Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested whether luteolin, a natural supplement found in celery and chamomile tea, can improve symptoms of schizophrenia. 85 adults with schizophrenia or schizoaffective disorder took either luteolin or a placebo for 12 weeks. Researchers measured changes in overall symptoms, thinking abilities, and markers of inflammation and oxidative stress.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: luteolin (a natural supplement found in foods like celery and chamomile tea)
What this could lead to: If it works, luteolin could offer a natural, add-on option to help ease schizophrenia symptoms.
What could go wrong: This is a small, completed trial with no phase designation. The supplement may not outperform placebo, and results may not apply to everyone with schizophrenia.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Psychotic Disorders schizoaffective disorder schizophrenia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

SCHIZOAFFECTIVE DISORDER SCHIZOPHRENIA

Contacts and locations

Locations

Maryland Psychiatric Research Center

Baltimore, Maryland, 21228, United States
University of California, Los Angeles

Los Angeles, California, 90095, United States

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