Could a celery compound help schizophrenia?
NCT ID NCT05204407
First seen Nov 01, 2025 · Last updated Jun 23, 2026 · Updated 37 times
Summary
This study tested whether luteolin, a natural supplement found in foods like celery and chamomile tea, can improve symptoms in people with schizophrenia or schizoaffective disorder. 85 clinically stable adults took either luteolin or a placebo for 12 weeks while continuing their usual antipsychotic medication. Researchers measured changes in overall symptoms, thinking abilities, and markers of inflammation and oxidative stress.
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Maryland Psychiatric Research Center
Baltimore, Maryland, 21228, United States
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University of California, Los Angeles
Los Angeles, California, 90095, United States
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
luteolin (a natural supplement found in celery, green pepper, parsley, and chamomile tea)
What this could lead to
If it works, luteolin could offer a natural way to ease schizophrenia symptoms when added to standard antipsychotic treatment.
What could go wrong
This is a small, completed trial with 85 people. The supplement may not outperform placebo, and results may not apply to everyone with schizophrenia.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.