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Smaller breaths on the ventilator may shield lungs during stomach surgery

NCT ID NCT07823816

Prevention Sponsor: University Medical Center Ho Chi Minh City (UMC) Source: ClinicalTrials.gov ↗

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only This study
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
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Status unknown
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First seen Sep 16, 2026 · Last updated Sep 17, 2026 · Updated 1 time

Summary

Researchers are studying whether using gentler ventilator settings during laparoscopic stomach surgery can protect patients' lungs. Adults scheduled for this operation receive either standard ventilation or a lung-protective strategy with smaller breaths and steady airway pressure. The team tracks oxygen levels, lung mechanics, and breathing complications after surgery to see if the protective approach makes a difference.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Lung-protective ventilation, a breathing-machine strategy using smaller breaths and steady airway pressure during surgery
What this could lead to
If it works, this approach could become a standard way to protect patients' lungs during abdominal surgery and reduce breathing problems afterward.
What could go wrong
The trial is small and single-center, so its results may not apply to all patients or hospitals. Ventilation settings that help one group might not help another, and the study may not show a clear difference.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 102 people

The number the study aims to enrol. It can still change while the study runs.

Started

Dec 2025

Expected to finish

Dec 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 70 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age 18-70 years scheduled for elective laparoscopic gastrectomy with ananticipated operative time \> 3 hours. * American Society of Anesthesiologists (ASA) physical status I-III. * Body mass index (BMI) \< 30 kg/m². Exclusion Criteria: * Gestational diabetes mellitus or pre-existing (chronic) diabetes mellitus * Gestational hypertension or chronic hypertension * Body mass index (BMI) ≥ 35 kg/m² * Known allergy to dexamethasone * Current long-term corticosteroid therapy * Diagnosis of postpartum hemorrhage

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Conditions

The condition(s) this trial relates to.

Pulmonary Atelectasis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Atelectasis Postoperative pulmonary complications (PPCS)

How to take part

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  1. The places running it

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  2. The official record

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Contacts and locations

Locations

  • University Medical Center HCMC

    Ho Chi Minh City, Ho Chi Minh, 700000, Vietnam

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