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Radiation-Free lung MRI could change how we diagnose scarring lung disease

NCT ID NCT03078426

Diagnosis Sponsor: University Hospital, Bordeaux Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested whether a special lung MRI can replace CT scans for diagnosing idiopathic pulmonary fibrosis (IPF), a scarring lung disease. Researchers compared MRI to standard CT in 60 patients to see if MRI could spot the same key signs of IPF without using radiation. The goal is to offer a safer, non-invasive imaging option for people with this condition.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
MRI scan
What this could lead to
If successful, MRI could become a radiation-free alternative to CT scans for diagnosing and monitoring idiopathic pulmonary fibrosis.
What could go wrong
This is a small, completed study (60 participants) comparing MRI to the standard CT. MRI may not be as accurate, and results may not apply to all patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

60 people

The number who actually took part.

Started

Feb 2017

Finished

Feb 2020

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patients \> 18 years old followed in Bordeaux University Hospital * Patients with a definite diagnosis of IPF : * Based on a "certain" UIP pattern at HRCT without histopathology * Based on a "possible" UIP pattern at HRCT with histopathology given by surgical lung biopsy. * Patients with a diagnosis of fibrosing sarcoidosis after multidisciplinary discussion * Patients with a diagnosis of acute or sub-acute hypersensitivity pneumonitis after multidisciplinary discussion * Patients diagnosed with organizing pneumonia after multidisciplinary discussion * Patients with a diagnosis of isolated pleural plaques after multidisciplinary discussion * Patient able to withstand supine position for more than 30 minutes * Patient affiliated to a social security system * Patients who gave their written informed consent Exclusion Criteria: * Subject detained by judicial or administrative decision. * Major protected by law. * Subject not affiliated to a social security care * Subject in period of relative exclusion in relation to another protocol. * Patients with specific contraindication to undergoing MRI: iron material, a heart pacemaker, claustrophobia, gadolinium hypersensitivity, renal impairment with glomerular filtration rate less than 30 mL/min, pregnant or nursing woman.

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Conditions

The condition(s) this trial relates to.

cryptogenic organizing pneumonia hypersensitivity pneumonitis idiopathic pulmonary fibrosis sarcoidosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Idiopathic pulmonary fibrosis

Contacts and locations

Locations

  • CHU de Bordeaux

    Pessac, 33604, France

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