Could a lung MRI replace scans and biopsies for smokers?

NCT ID NCT06825078

First seen Jul 09, 2026 · Last updated Jul 10, 2026 · Updated 1 time

Summary

This study tests whether a special lung MRI, combined with a computer-generated CT-like image, can accurately detect lung cancer in heavy smokers. Participants are 55–74 years old with a solid lung nodule found on a prior scan. The goal is to see if this non-invasive method can reduce false alarms and the need for risky biopsies.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
multiparametric MRI and synthetic CT
What this could lead to
If successful, this approach could offer a safer, non-invasive way to monitor lung nodules and reduce unnecessary biopsies in high-risk smokers.
What could go wrong
This is a small pilot study (50 people) at a single center, so results may not apply broadly. MRI may miss some nodules or yield false positives.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • CHU Bordeaux

    RECRUITING

    Pessac, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

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