New study aims to catch lung cancer earlier in smokers

NCT ID NCT06376097

Recruiting now Diagnosis Sponsor: AstraZeneca Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Aug 04, 2026 · Updated 5 times

Summary

This study is testing a lung cancer screening program for smokers aged 45 to 74. It uses low-dose CT scans and metabolomics to find lung nodules and reduce false negatives. The goal is to improve early detection and help smokers quit. 1,000 participants will be followed in a public health service.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this could lead to a more effective lung cancer screening method that catches cancer earlier and reduces unnecessary biopsies.
What could go wrong: This is an observational study, not a treatment trial. It may not prove that screening improves survival, and false positives or negatives could still occur.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

lung cancer lung neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

LUNG CANCER

Contacts and locations

Locations

Hospital das Clínicas da Faculdade de Medicina de Botucatu (HCFMB)
RECRUITING

Botucatu, São Paulo, 18618-686, Brazil

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