No-Marker tumor tracking could make lung cancer radiation safer

NCT ID NCT04310891

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests a new X-ray technique to track lung tumors during radiation without needing implanted markers. Five adults with early-stage lung cancer will be observed to see if the markerless method matches the standard marker-based tracking within 3 millimeters. If it works, it could make radiotherapy less invasive and more comfortable.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Markerless Tumour Tracking (intrafraction kilovoltage X-ray imaging)

What this could lead to

If successful, this could make lung cancer radiotherapy more accurate and less invasive by removing the need for implanted markers.

What could go wrong

This is a very small, early-phase study with only 5 participants, so results may not apply to all patients. The tracking method may not be accurate enough for routine use.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

lung cancer lung neoplasm non-small cell lung carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Royal North Shore Hospital

    Saint Leonards, New South Wales, 2065, Australia