New drug cocktail shows promise for Hard-to-Treat lung cancer before surgery
NCT ID NCT05118854
First seen Jun 27, 2026 · Last updated Jul 02, 2026 · Updated 2 times
Summary
This study is for people with a specific type of lung cancer (non-squamous non-small cell) that has a KRAS G12C mutation and can be removed with surgery. It tests whether giving a targeted drug (sotorasib) plus standard chemotherapy before surgery can shrink the tumor more than chemotherapy alone. About 27 adults will take part, and the main goal is to see how many tumors show a major response after treatment.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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M D Anderson Cancer Center
Houston, Texas, 77030, United States
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Memorial Sloan Kettering Cancer Center
New York, New York, 10065, United States
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