New laser imaging aims to spot lung cancer in real time

NCT ID NCT05556525

Terminated Diagnosis Sponsor: Mayo Clinic Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 26, 2026 · Updated 1 time

Summary

This study tested whether adding a special laser imaging technique (nCLE) and a dye (fluorescein) to a standard needle biopsy could help doctors diagnose lung cancer more accurately. The plan was to compare the combined approach to the standard biopsy alone in people with suspicious lung nodules. However, the trial was stopped early after enrolling only 3 participants, so it did not produce meaningful results.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Fluorescein
What this could lead to: If successful, this approach could improve the accuracy of lung cancer diagnosis during a single procedure, reducing the need for repeat biopsies.
What could go wrong: The trial was terminated early with only 3 participants, so no reliable conclusions can be drawn. The technique is still experimental and may not work better than standard methods.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

lung cancer lung carcinoma lung neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

LUNG CARCINOMA

Contacts and locations

Locations

Mayo Clinic in Florida

Jacksonville, Florida, 32224-9980, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.